The Matrix Biology Institute (MBI) was founded in 1982 by Endre A. Balazs, M.D. and Janet L. Denlinger, Ph.D. At that time both of them were members of the faculty of the Eye Research Department at the College of Physicians and Surgeons of Columbia University in New York. Endre Balazs, Professor Emeritus of Columbia University of New York is the Chief Scientific Officer and Chair of the board of MBI, and Janet Denlinger is the President.
The objective of MBI is to carry out research on the structure, function and therapeutic use of hyaluronic acid, one of the molecular building blocks of the intercellular matrix. Since its inception, MBI has carried out and supported research projects on the biological function of the intercellular matrix (biomatrix). The results of this research are published in international research.